learn-ai-research-with-phoebe / Leader session 2 of 6
Learn AI Research with Phoebe · Leader track · Session 2 of 6

The evidence standard you share

Ask three researchers on your team what "strong evidence" means and you will get three answers - and you will only find out on the day a client disagrees with the fourth. Tonight we fix that with a rulebook that fits on one page: four source tiers tagged at the moment of capture, four certainty levels with definitions nobody has to interpret, and the honest news about the evidence hierarchy you were taught, which the people who use it professionally revised a decade ago. None of this is new. Clinical evidence teams had this argument first and wrote down the answer. Your job is to borrow it, not to reinvent it.

🟢 Leader track Research · insights · strategy leads The shared rulebook 45 min
0-2 · Why one page beats good intentions 2-16 · The four tiers 16-34 · Certainty, and the honest hierarchy 34-45 · Publish your standard
Part 1 · the rulebook

Four tiers, and one hard rule 8 min live

A source tier is not a compliment or an insult. It is a statement about how much weight a source can bear on its own, decided before anyone has an opinion about the conclusion. Four tiers is the right number: fewer and everything collapses into "credible" and "not credible", more and nobody uses it. Tier 1 is peer-reviewed synthesis, randomised trials, and statute or regulator text. Tier 2 is peer-reviewed empirical work and official statistics. Tier 3 is analyst reports, trade press and preprints. Tier 4 is vendor blogs, press releases and forum posts. And then the one rule that gives the whole system teeth: a claim resting only on tier 4 fails, however many tier-4 sources happen to agree with each other. Agreement among promotional material is not corroboration; it is the same press release travelling.

TIER WHAT IS IN IT WHAT IT MAY CARRY TYPICAL EXAMPLE TIER 1 Peer-reviewed synthesis, RCTs, statute, regulator text A load-bearing claim, on its own A Cochrane review, an Act, a published regulator rule TIER 2 Peer-reviewed empirical work, official statistics A claim, with its population stated A journal study of 400, a national census table TIER 3 Analyst reports, trade press, preprints Context and direction, not a decision A market-size estimate with no method attached TIER 4 Vendor blogs, press releases, forum posts Nothing a decision rests on "99% accurate" with no methodology published Tag the tier at capture, in the same keystroke as the link. Retro-tagging lets wishful thinking in. A claim resting only on tier 4 fails, however many tier-4 sources agree with each other.
🔍 Click to zoom - four tiers, what each may carry, and the rule with teeth
LiveWhy tagging at capture is the whole discipline4 min▶

Tiering is trivially easy to write down and surprisingly hard to run, and the failure always happens in the same place: the tag gets applied after the conclusion exists. Once a researcher believes the answer, a vendor case study starts to feel like tier 3, a preprint starts to feel like tier 2, and nobody is lying - the tier just quietly drifts toward whatever the argument needs.

So make it mechanical:

  • Tier is recorded in the same action as the link. If the row has a URL and no tier, the row is not finished. This is a two-second habit that removes an entire class of argument later.
  • Tier is a property of the source, not of the claim. A vendor blog is tier 4 when it agrees with you and tier 4 when it does not.
  • Never retro-tag a whole batch. Bulk tagging at the end of a project is indistinguishable, on the file, from having decided the answer first.
  • Publishing venue is not authorship. A vendor-funded study in a peer-reviewed journal is tier 2 with the funder recorded, not tier 4 - and the funder column is why you record funders.

One more leader-grade nuance. Tier 3 is not a rubbish bin. Analyst reports and preprints are frequently the only source of a market number that exists, and the honest handling is to use them for direction and say so in the sentence: "analyst estimates put this in the region of X; no peer-reviewed figure exists". That sentence is defensible. "The market is X" over the same source is not.

Self-studyWhat the tiers do to an AI-assisted search3 min read▶

Tiering matters more now than it did five years ago, for a specific structural reason: the ranking that surfaces sources is not sorted by tier. Vendor content is written to be found - clean headings, direct answers, generous keyword coverage - and regulator text and peer-reviewed synthesis are written to be correct. When a tool retrieves and summarises in one motion, the tier distribution of what comes back is a property of the index, not of your question.

The practical consequence for a leader is that an untiered AI search tends to produce a tier-3-and-4 evidence base with tier-1 confidence in the prose. The fluency is uniform; the underlying weight is not. Tiering is the cheapest available correction, because it makes the distribution visible: count the rows by tier before you read the conclusion, and you will know in ten seconds whether this is a decision-grade base or a market-narrative one.

In the researcher track's live audit, turning source tiering on is the rung that takes the source count from 9 to 22 - not because 22 is a magic number, but because that is when the peer-reviewed and regulator sources finally arrive. They were always there. Nothing had gone looking for them.

Part 2 · certainty with definitions

Certainty, done properly 9 min live

"Strong evidence" is not a certainty level. It is a feeling with a formal-sounding name. The clinical world hit this problem decades before insights teams did, and the answer they built is GRADE: four levels, each with a written definition, and an explicit list of the things that push a body of evidence up or down. You do not have to adopt GRADE wholesale to benefit from it. What you should steal is the discipline underneath it - a certainty word means the same thing to everyone, and moving between words requires a named reason.

LiveGRADE's four levels, and where a body of evidence starts4 min▶

GRADE rates the certainty of a body of evidence, not of a single study, at four levels. Two of the definitions are worth having verbatim, because the wording is the point:

LevelWhat it means
High"We are very confident that the true effect lies close to that of the estimate"
ModerateConfidence is meaningful but the true effect may differ from the estimate
Low"Our confidence in the effect estimate is limited"
Very lowVery little confidence in the estimate at all

Notice what the High definition is about: the distance between the estimate and the truth. It is not about how impressive the study was, or how many sources agreed, or how confident the author sounded. That is the shift to teach your team.

Then the starting points, which are the part people find genuinely surprising: a body of randomised-trial evidence starts at High. A body of observational evidence starts at Low. You do not begin neutral and argue your way up. You begin at the level the study design earns and then move for named reasons. For a commercial insights team the translation is immediate: almost everything you work with - surveys, panels, analytics, interviews, market data - is observational, so your default starting point is Low, and every step above it needs to be argued. That single sentence changes how a lot of decks get written.

LiveThe five reasons to downgrade, and the three to upgrade4 min▶

Movement between levels is not vibes. GRADE names five downgrading factors:

  • Risk of bias - how the studies were run and reported.
  • Inconsistency - the studies disagree with each other more than chance explains.
  • Indirectness - the population, intervention or outcome is not the one you actually care about. This is the one that bites hardest in commercial research, where the available study is nearly always about a slightly different population.
  • Imprecision - the interval is wide enough that opposite decisions sit inside it.
  • Publication bias - what got published is not what got studied.

And three upgrading factors, which apply to non-randomised evidence only:

  • Large effect - the magnitude is big enough that plausible confounding cannot explain it.
  • Residual confounding that would reduce the effect - the biases you can identify all point the other way, so the true effect is probably at least this big.
  • Dose-response gradient - more of the input, more of the output, in an orderly way.

Run this as a leader by asking one question in reviews: "which factor moved this, and in which direction?" If the answer is a factor name, the certainty word is earned. If the answer is a tone of voice, it is not.

LiveCochrane RoB 2 - and the two rules that transfer everywhere3 min▶

Risk of bias has its own instrument, Cochrane's RoB 2, and two of its design choices are worth borrowing even if you never fill in the tool itself.

First: it is assessed per result, not per study. The same paper can be low risk for its primary outcome and high risk for a secondary one, so "this study is good" is not a statement RoB 2 can make. For your team, that kills the most common shortcut in AI-assisted synthesis - treating a paper as a unit of credibility and then citing whichever number inside it is convenient.

The five domains it assesses, in order: the randomisation process; deviations from intended interventions; missing outcome data; measurement of the outcome; selection of the reported result. Each gets one of three judgements: low risk, some concerns, or high risk.

Second: the overall judgement is effectively the least favourable domain. Four clean domains and one high-risk domain does not average to "some concerns". This is the rule to import wholesale into your own standard, because it is the exact opposite of how most decks are built. A claim is as strong as its weakest load-bearing link, not as strong as the average impression of its evidence - and the hostile reader from a1 will find the weakest link, not the average.

Part 3 · the honest version

The hierarchy, and its published critique 7 min live

Most people carry a mental pyramid: systematic reviews and meta-analyses on top, then randomised trials, non-randomised trials, cohort, case-control, cross-sectional, case series, expert opinion at the bottom. It is a useful first sort and you should know it. But the people who use it professionally revised it, in print, and the revision is the part that makes you a better reader. Murad MH et al., "New evidence pyramid," Evid Based Med 2016;21(4):125-7 changes it in two ways: the straight lines between designs become wavy, because a well-run cohort study can outrank a badly-run trial, and systematic reviews come off the apex entirely to become, in their phrase, "a lens through which evidence is viewed".

CONVENTIONAL HIERARCHY straight lines, review on the apex Systematic reviews RCTs Non-randomised trials Cohort studies Case-control studies Cross-sectional Case series and reports Expert opinion Useful first sort. Not an appraisal. MURAD 2016 - REVISED wavy lines, review becomes a lens SYSTEMATIC REVIEW = A LENS, NOT THE APEX RCTs Non-randomised trials Cohort studies Case-control studies Cross-sectional Case series and reports Expert opinion A good cohort can outrank a weak trial. Murad et al. 2016: the lines between designs go wavy, and the review moves off the apex to be a lens. A credible review can summarise biased evidence. So a design label is never an appraisal on its own.
🔍 Click to zoom - the pyramid you were taught, beside the one its own field published
LiveWhy the review came off the apex4 min▶

Murad and colleagues' core argument is one sentence long, and it is the most useful sentence in this session: "credible systematic review can summarize biased evidence and poorly done systematic reviews can summarize well done trials". Both halves matter. A rigorous review of a weak literature is still a weak evidence base - the rigour is in the method, not in the underlying studies. And a sloppy review of excellent trials wastes the trials.

So the review is not a higher grade of evidence. It is an instrument for looking at evidence - a lens, in their word - and the quality of the picture depends on both the lens and the thing being looked at. That is why they moved it off the top and drew it as something you view the pyramid through.

The wavy lines make the companion point. A design label sets a prior, not a verdict. A large, well-run cohort study with a pre-registered analysis can carry more weight than a small trial with high dropout and a swapped primary outcome, and the straight-lined pyramid has no way to express that. Waviness is how you draw "appraisal beats label".

The leader takeaway, and the line to say out loud in your next review: a design label is not an appraisal. "It is a meta-analysis" is the beginning of the conversation. What is inside it, how it was run, and whether its included studies would survive their own appraisal is the conversation.

Self-studyHow this changes what you accept in a deck3 min read▶

Three habits follow directly, and all three are cheap:

  • Stop accepting design labels as quality claims. When a slide says "based on a systematic review", the follow-up is "of what, and how many of the included studies were any good?" This is not scepticism for its own sake - it is the question the source's own field says you should ask.
  • Separate the tier from the appraisal in your own standard. Tier says what a source may carry structurally. Appraisal says what this particular source, on this particular result, actually earned. Two columns, not one, and the second is where the RoB 2 least-favourable-domain rule lives.
  • Treat "peer-reviewed" as a floor, not a ceiling. It clears tier 1 or 2 and tells you nothing about risk of bias, indirectness or imprecision. A funder-conflicted study of the wrong population is peer-reviewed and still nearly useless for your decision.

This is also the answer to a question leaders ask about AI-assisted synthesis: why is a fluent, well-cited summary still not enough? Because a summary reports labels. Labels are cheap to produce and cheap to read, and appraisal is neither.

Part 4 · publish it

The one-page standard you give your team 9 min live

Everything above collapses into four things on one page. Write them, put your name on them, and hand them out. The value is not in the sophistication - it is in the fact that everyone is holding the same page, so disagreements become about the evidence rather than about whose instinct is better.

LiveItem 1 - tier tags, applied at capture2 min▶

Four tiers as in Part 1, written out with two or three examples each so nobody has to interpret them. Then three lines of policy:

  • The tier is recorded when the source is captured. A row with a link and no tier is unfinished.
  • The tier belongs to the source, not to the argument, and it does not move.
  • A claim resting only on tier 4 does not ship. Not softened - not shipped.

Add a funder column while you are there. It costs nothing at capture and it is the difference between "a peer-reviewed study found" and "a vendor-funded peer-reviewed study found", which are two different sentences.

LiveItem 2 - a certainty word list with agreed meanings3 min▶

Pick four words, define each in one line, and forbid everything else. A plain-language version that maps cleanly onto GRADE:

Word we useWhat it means hereWhat it requires
EstablishedWe are very confident the true effect is close to our estimateTier 1 or 2, consistent, on our population, and nothing downgrading it
IndicatedProbably true; the estimate may differ from the truthSolid sources with one named downgrade, usually indirectness
LimitedOur confidence in the estimate is limitedObservational or thin; state the sample and the caveat in the same sentence
UnknownWe could not settle this, and here is the test that wouldNothing in our set supports it; say so and price the test

Two rules make the list real rather than decorative. Every certainty word is accompanied by the reason it moved - a factor name from Part 2, not a tone. And "Unknown" is a permitted, respectable output. If your culture punishes it, your team will write "Limited" over nothing, which is the failure this whole standard exists to prevent. In the researcher track's audit, the tenth claim never survives at any setting, and the correct answer for it is exactly this word.

LiveItem 3 - the eight extraction columns2 min▶

Every claim that carries a number needs a row, and the row has eight columns:

ColumnWhy it is there
SourceThe thing itself, tiered, so the claim can be traced
YearA 2016 market number is not a current market number
Samplen=48 and n=4,800 support very different sentences
MeasureWhat was actually measured, not what it was called
NumberThe figure, as stated, before anyone rounds it
PageSo the next person can check in ten seconds
FunderInterest is not disqualifying, but it is context
PopulationThe indirectness check: is this even our market?

And then the rule that makes the table worth keeping: a number without a recorded row does not go in a deck. No exceptions for numbers that feel obvious, and none for numbers under time pressure - those are precisely the ones that turn out to be from a blog post quoting a webinar quoting nothing.

Self-studyItem 4 - the request you send, and the one you should not3 min read▶

The standard also governs how work is commissioned, because a vague brief cannot produce a defensible answer no matter how good the standard is downstream. Compare the two requests a leader might send about the Cadence decision:

Vague - cannot come back negative

"Look into the higher-education market for AI note-taking and summarise the key trends, drivers and opportunity size. Include the main players and any regulatory considerations."

Decision-scoped - each claim could be false

"We decide in three weeks whether to build lecture notes for higher education. Test these claims, each of which could come back false: (1) institutions, not students, hold the budget; (2) recording lectures requires documented consent in both target markets; (3) procurement runs 6 to 12 months; (4) our meeting-notes engine transfers to lecture audio without retraining. For each: strongest evidence for, strongest evidence against, the tier of every source, and what you could not find. Tell me which claim is weakest and why."

The first brief will come back looking excellent and will not be able to tell you no. The second can come back "claim 4 is unsupported" - the most valuable sentence in the whole project, and one the first brief structurally cannot produce. Note the last two clauses especially: asking what could not be found turns silence into information, and asking which claim is weakest forces someone to read the work the way the hostile reader from a1 will.

★ What you walk out with today Four source tiers with the tier-4 rule, four certainty words with definitions borrowed from GRADE, the eight extraction columns and the no-row-no-number rule, RoB 2's least-favourable-domain principle, and one sentence that will change how you read decks for good: a design label is not an appraisal.
What this course does not cover, by design Catching fabricated citations - the confident reference to a paper that does not exist - belongs to the sibling AI + Law course. This course owns the question a tier tag and an extraction row are built to answer: does a real source actually support the sentence written on top of it?
Homework

Try it yourself - this week ◐ 35-45 min total

Source material

Official sources covered

This session teaches the working core of the established evidence-appraisal standards, quoted from the bodies that publish them. The normative documents stay with their owners and are linked in session. This page covers:

✓GRADE - four certainty levels, starting points, five downgrades, three upgradesPart 2 · High and Low definitions quoted verbatim from the GRADE handbook
✓Cochrane RoB 2 - per result, five domains, least-favourable overallPart 2 · the two design choices that transfer to commercial research
✓Murad et al., "New evidence pyramid," Evid Based Med 2016;21(4):125-7Part 3 · wavy boundaries, and the review as a lens rather than the apex
✓The four-tier source system and the extraction columnsParts 1 and 4 · the practical layer your team runs day to day
◐PRISMA 2020 - reporting, not appraisalNamed here as a reporting guideline · the flow and screening log in b4
Check yourself

Three questions before you go 🎯 ◐ 90 seconds

1 · Which of these is GRADE's list of downgrading factors?

Those five are the downgrades. Option B is the three upgrading factors, and they apply to non-randomised evidence only. The habit to build is asking which named factor moved a certainty word, and in which direction - a factor name earns the word, a tone of voice does not.

2 · Cochrane RoB 2 is assessed per result rather than per study. Why does that matter to a research leader?

Per-result assessment kills the most common shortcut in AI-assisted synthesis: treating a paper as a unit of credibility and then citing whichever number inside it is convenient. And the overall judgement is effectively the least favourable domain, not an average - four clean domains plus one high-risk domain is not "some concerns".

3 · What did Murad et al. (2016) change about the evidence pyramid?

Their core argument is that a credible systematic review can summarise biased evidence, and a poorly done review can summarise well done trials - so the review is an instrument for looking at evidence, not a higher grade of it. Waviness makes the companion point that appraisal beats label. Hence the line to repeat: a design label is not an appraisal.

Leader session 2 cheat sheet · pin this

The four tiers1 peer-reviewed synthesis, RCTs, statute and regulator text · 2 peer-reviewed empirical and official statistics · 3 analyst, trade press, preprints · 4 vendor blogs, releases, forums.
The rule with teethA claim resting only on tier 4 fails. Tag the tier at capture, in the same keystroke as the link - never retro-tag.
GRADE, four levelsHigh: "very confident that the true effect lies close to that of the estimate". Low: "our confidence in the effect estimate is limited".
Where you startRandomised bodies start High, observational start Low. Almost all commercial insight is observational, so your default is Low.
Five down, three upDown: risk of bias, inconsistency, indirectness, imprecision, publication bias. Up (non-randomised only): large effect, residual confounding, dose-response.
RoB 2Per result, not per study. Five domains. Overall is effectively the least favourable domain - never an average.
Murad 2016Wavy lines between designs, review off the apex as a lens. A design label is not an appraisal.
Eight columnsSource, year, sample, measure, number, page, funder, population. No recorded row means the number does not go in a deck.